Posaconazole efficacy in a murine disseminated infection caused by Paecilomyces lilacinus
نویسندگان
چکیده
منابع مشابه
Efficacy of posaconazole in a murine model of disseminated infection caused by Apophysomyces variabilis.
OBJECTIVES We evaluated the in vitro activity of posaconazole and amphotericin B against several clinical strains of the mucoralean fungus Apophysomyces variabilis, and their efficacy in a murine model of disseminated infection caused by that fungus. METHODS The in vitro susceptibility of seven strains of A. variabilis to posaconazole and amphotericin B was determined by using a broth microdi...
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Invasive fungal infections of the sinonasal tract are a rare but known entity in immunocompromised patients. Paecilomyces lilacinus is a nematophagous fungi with septate hyphae that has afflicted humans in multiple forms, causing cutaneous, ocular, and sinonasal infections. Only 4 cases of P lilacinus and 2 cases of Paecilomyces variotii in the sinonasal tract have been reported in the literatu...
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Effects of rice-cultured Paecilomyces lilacinus on Rotylenchulus reniformis were studied in both greenhouse and field microplot tests with 'Rutgers' tomato. Numbers of R. reniformis were reduced (P </= 0.05) by P. lilacinus, with suppression in the initial greenhouse test ranging from 46 to 48% for two rice + P. lilacinus treatments; the rice-only treatment caused a nonsignificant reduction of ...
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متن کاملEfficacy of posaconazole in murine experimental sporotrichosis.
We developed a murine model of systemic sporotrichosis by using three strains of each of the two commonest species causing sporotrichosis, i.e., Sporothrix schenckii sensu stricto and Sporothrix brasiliensis, in order to evaluate the efficacy of posaconazole (PSC). The drug was administered at a dose of 2.5 or 5 mg/kg of body weight twice a day by gavage, and one group was treated with amphoter...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2008
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkn497